MCAT Games
Free interactive games for every AAMC MCAT content category. 153 topic-specific games - Biochemistry, Bio/Molecular, Gen Chem, Org Chem, Physics, Psych/Soc - all built around active recall.
This is not a passive review hub. Every game forces you to actually retrieve enzymes, formulas, brain regions or constants under game conditions. That is the same retrieval cognitive science research keeps ranking as the strongest single study strategy ever measured.
Biochemistry - Metabolism & Molecules
Amino acids, protein structure, enzyme behavior, every metabolic pathway worth memorizing. The single highest-yield MCAT cluster.
Glycolysis Game
LiveAll 10 steps, key enzymes, regulation, ATP/NADH yield.
Play tournamentGluconeogenesis Game
LiveBypass enzymes, hormonal regulation, Cori cycle integration.
Play tournamentGlycogenesis & Glycogenolysis Game
LiveGlycogen synthase, phosphorylase, branching/debranching enzymes.
Play tournamentCitric Acid Cycle (Krebs) Game
LiveSubstrates, enzymes, NADH/FADH2/GTP/CO2 output per turn.
Play tournamentPyruvate Dehydrogenase Complex Game
LivePDC mechanism, the five cofactors, PDK/PDP regulation, arsenite + thiamine.
Play tournamentElectron Transport Chain Game
LiveComplexes I-IV, electron donors, proton pumping, inhibitors.
Play tournamentOxidative Phosphorylation Game
LiveATP synthase mechanism, P/O ratio, chemiosmotic coupling.
Play tournamentPentose Phosphate Pathway Game
LiveNADPH production, ribose-5-P, oxidative vs. non-oxidative phase.
Play tournamentFatty Acid Oxidation Game
LiveBeta-oxidation, carnitine shuttle, acetyl-CoA yield, ketogenesis.
Play tournamentFatty Acid Synthesis Game
LiveAcetyl-CoA carboxylase, FAS multienzyme, NADPH requirement.
Play tournamentKetone Body Metabolism Game
LiveKetogenesis, ketolysis, β-OH-butyrate, DKA biochemistry, MCAD.
Play tournamentCholesterol Biosynthesis Game
LiveHMG-CoA reductase, mevalonate, statin mechanism, LDLR upregulation.
Play tournamentUrea Cycle Game
LiveCPS I, OTC, NAG regulation, hyperammonemia, ammonia scavengers.
Play tournamentAmino Acid Catabolism & Inborn Errors Game
LivePKU, alkaptonuria, MSUD, homocystinuria - the classic IEMs.
Play tournamentHeme Biosynthesis & Porphyrias Game
LiveALA synthase, the 8-step pathway, lead poisoning, AIP, PCT, ferrochelatase.
Play tournamentPurine Metabolism Game
LivePRPP, salvage, Lesch-Nyhan HGPRT, allopurinol, tumor lysis, ADA-SCID.
Play tournament
Molecular Biology & Genetics
Central dogma, replication, transcription, translation, regulation - plus inheritance, viruses, cell cycle and evolution.
Meiosis & Genetic Variability Game
LiveCrossing over, independent assortment, meiosis I vs. II.
Play tournamentDNA Replication Game
LiveHelicase, polymerases, Okazaki fragments, leading vs. lagging strand.
Play tournamentTranscription Game
LiveRNA polymerase, promoter, mRNA processing, splicing, capping.
Play tournamentTranslation Game
LiveRibosomes, tRNA, codon-anticodon, initiation/elongation/termination.
Play tournamentDNA Repair Mechanisms Game
LiveMMR (Lynch), NER (XP), BER, HR vs. NHEJ, BRCA + PARP synthetic lethality.
Play tournamentWnt Signaling Game
Liveβ-catenin destruction complex, APC + colorectal cancer, sclerostin/DKK1.
Play tournamentNotch Signaling Game
LiveDelta/Jagged ligands, S2/S3 cleavage, NICD, T-ALL, Alagille syndrome.
Play tournamentHedgehog Signaling Game
LivePatched + Smoothened, primary cilium, GLI, vismodegib + basal cell carcinoma.
Play tournamentCell Cycle & Mitosis Game
LiveG1, S, G2, M phases, checkpoints, cyclin/CDK regulation.
Play tournamentApoptosis Game
LiveIntrinsic vs. extrinsic, Bcl-2 family, cytochrome c, caspase cascade.
Play tournament
Human Physiology - Organ Systems
Every organ system the MCAT loves to ask about - nervous, endocrine, cardio, respiratory, renal, immune, reproductive and beyond.
GPCR Signaling Game
LiveGαs/Gαi/Gαq, cAMP/PKA, IP3/DAG, cholera & pertussis toxin.
Play tournamentMAPK / Ras Signaling Cascade Game
LiveGrb2-SOS-Ras-Raf-MEK-ERK, BRAF V600E in melanoma, NF1 RASopathy.
Play tournamentInsulin & RTK Signaling Game
LiveIRS-1/2, PI3K-Akt-mTOR, GLUT4, T2DM insulin resistance, PTEN.
Play tournamentHemostasis & Coagulation Cascade Game
LivePrimary + secondary hemostasis, vitamin K factors, hemophilia, DIC, warfarin/heparin.
Play tournamentInnate Immunity & TLR Signaling Game
LiveTLR4/LPS, MyD88-NF-κB, septic shock, inflammasome, type I interferons.
Play tournamentComplement Cascade Game
LiveClassical/lectin/alternative, C3 convertase, MAC, C1-INH/HAE, PNH/eculizumab.
Play tournament
General Chemistry
Atomic structure to thermodynamics to electrochemistry. The MCAT's most computational discipline - drilled to instinct.
Organic Chemistry
Reactions, mechanisms, isomerism, separations and spectroscopy - the high-yield slice the MCAT actually tests.
Physics
Mechanics, fluids, electricity, optics, waves, nuclear - every formula the MCAT expects you to apply on sight.
Psychology
Brain, sensation, learning, memory, cognition, emotion, personality, disorders - the entire P/S psychology block.
Sociology
Sociological theories, institutions, demographics, group dynamics, stratification - the entire P/S sociology block.
The Complete MCAT Game Library - Every Topic, Every Content Category
The MCAT does not test trivia. It tests whether you can recognize a metabolic intermediate, apply a physics equation, decode a Punnett square or differentiate two competing personality theories under time pressure. That recognition speed is built only one way: thousands of small retrieval reps across every single content topic the AAMC publishes. Lorea's MCAT game library is engineered exactly for that - 153 short, focused, single-topic games covering the full Biological & Biochemical Foundations, Chemical & Physical Foundations, and Psychological, Social & Biological Foundations of Behavior outlines.
Every game lives at its own permanent URL - for example /exam-games/mcat/glycolysis-game or /exam-games/mcat/action-potentials-game. That gives you something a 1,200-page review book physically cannot: a bookmarkable, shareable, study-group-ready entry point for every single concept on the test. Drop the link in your discord. Pin it on your bookmark bar. Open it on the bus. Beat the game. Move on.
Why “a game per topic” beats “a chapter per topic”
Reading a chapter on glycolysis activates recognition memory - the comforting feeling of “yes, I've seen this.” That feeling is famously decoupled from actual exam performance. Playing a glycolysis game forces retrieval - generating the answer from cold storage. Retrieval practice repeatedly outperforms re-reading by 30-50% on delayed tests in controlled studies (Roediger & Karpicke; Dunlosky et al.). Stack 130 of those drills across 12 weeks and you have done what no review book can do.
How the AAMC content map lines up with this hub
- Biochemistry (Metabolism & Molecules) - covers Foundational Concept 1 (biomolecules) and 3 (metabolic pathways), plus C/P-aligned enzyme kinetics.
- Molecular Biology & Genetics - Foundational Concept 1 (replication, transcription, translation, regulation) and 2 (cellular organization, embryogenesis, evolution).
- Human Physiology - Foundational Concept 3 (organ systems) with neurophysiology overlap into P/S.
- General Chemistry - Foundational Concept 4 and 5 (atomic, thermodynamic, electrochemical principles).
- Organic Chemistry - Foundational Concept 4 and 5 with B/B overlap on biomolecule reactivity.
- Physics - Foundational Concept 4 and 5 (mechanics, fluids, electrostatics, optics, sound, nuclear).
- Psychology - Foundational Concept 6, 7 and 8 (sensation, learning, cognition, emotion, personality, disorders).
- Sociology - Foundational Concept 9 and 10 (social institutions, demographics, stratification, inequality).
Build your own MCAT game from your own notes
Have a Khan Academy PDF, a Kaplan chapter or your professor's lecture deck? Upload it to PDF to Game and Lorea will generate a fully playable MCAT-style game from that exact content. Pair the curated library above with a few custom games per week and you have an end-to-end retrieval engine for the entire AAMC outline.
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