Chapter 3 of 5 - Anatomy Course
The thorax protects heart and lungs; the abdomen houses digestive and major vascular structures. Serous membranes (pleura, peritoneum) reduce friction and define surgical planes.
Board questions often hinge on which cavity a structure occupies, whether infection can spread along continuous spaces, and landmarks for safe procedures.
The mediastinum sits between the pleural cavities. Superior versus inferior divisions and subdivisions (for example middle mediastinum housing the heart) organize lymph node maps and mass localization on CT.
The diaphragm separates thoracic and abdominal cavities; penetrating injuries can involve both. Phrenic nerve supply and diaphragmatic excursion matter for breathing mechanics and referred shoulder pain from diaphragmatic irritation.
Visceral pleura on lung
Moves with lung expansion.
Pleural cavity (potential)
Thin fluid layer; negative intrapleural pressure.
Parietal pleura on wall
Somatic pain fibers from chest wall sources.
Air or blood in cavity
Pneumothorax or hemothorax collapses or compresses lung.

Thoracic pleural cavities flank the mediastinum; the diaphragm separates thorax from abdominopelvic viscera. Use this map when localizing infection or free air.
Gas exchange links thoracic anatomy to physiology: alveolar-capillary diffusion sets arterial oxygen content carried by hemoglobin.
Formula
O2
Mol. Weight
31.998 g/mol
The peritoneum has parietal (lining abdominal wall) and visceral (covering organs) layers. The greater sac is the main cavity; the lesser sac (omental bursa) lies behind the stomach and communicates via the epiploic foramen (of Winslow).
| Region | Examples |
|---|---|
| Right upper quadrant | Liver, gallbladder, duodenal bulb (conceptual localization) |
| Left upper quadrant | Spleen, stomach body, tail of pancreas |
| Retroperitoneum | Kidneys, ureters, great vessels, pancreatic head (classic teaching) |
Quick Check
Which structure connects the greater and lesser peritoneal sacs?
Fill in the Blank
The serous membrane lining the abdominal cavity and covering most abdominal organs is the________.
Localize quadrant or epigastric region
RUQ pain suggests hepatobiliary differential first.
Parietal versus visceral pain
Wall irritation localizes; hollow organ distension is crampy.
Consider referred pain
Diaphragm to shoulder; ureter to groin.
Map adjacent retroperitoneal structures
Pancreatitis vs perforated ulcer patterns differ.
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